Developing Minimally Invasive Technologies to Treat Colorectal Diseases

Signum Surgical is committed to developing innovative solutions to treat patients with colorectal diseases, starting with anal fistula. 

After a year of exploring the needs of gastrointestinal and colorectal care, Eoin Bambury and Moshe Zilversmit founded the company in 2016 as a spin-out of the National University of Ireland, Galway, BioInnovate programme. The company is headquartered in Galway, Ireland.

Moshe Zilversmit


Medical device entrepreneur with over 12 years of experience in medical device development. Moshe released the world’s first open source surgical device, which has been covered by Wired magazine and recognised by Discover Magazine as one of the top innovations of 2013.

Eoin Bambury


Over 24 years of experience in the research and development of novel medical devices. Eoin has contributed to the development of six medical devices currently on the market and is a named inventor on 28 granted patent filings. Eoin was awarded ‘Chartered Engineer of the Year 2012’ by Engineers Ireland.

Board of Directors

Jeff Grainger

Jeff is an intellectual property specialist with more than 25 years of experience in early stage medtech companies.  Jeff previously served as a Managing Partner at  successful incubator The Foundry and holds a JD from the University of Washington and a BS in Mechanical Engineering from Stanford.

Bernard Collins

Dr Collins is a leading expert in the medical technology sector and serves on the Board of Directors of several US and Irish life-science companies. A former Vice President of International Operations for Boston Scientific, where he served for 10 years, Dr Collins has held a number of senior executive positions in international life-science companies during his career.

Alan Levy

Alan brings more than 40 years of experience in the medical device industry. Alan is involved with multiple life science companies as a CEO and as a board member and was a Senior Advisor to Frazier Healthcare Partners. Alan is an expert in bioabsorbable materials and the inventor of Vicryl, an absorbable surgical suture. 

Liam Farrissey

Liam has held a number of senior technical, commercial and business development roles in the medical device industry over the past 20 years. He brings strong experience in commercialising medical devices having worked closely with start-ups, multinational companies and “own design” products. Liam is the CEO of CrannMed, a Galway-based company focused on developing next generation resorbable embolization technologies.

Scientific Advisory Board

Dr. Madhulika Varma, MD

Dr. Madhulika (Mika) Varma, chief of colorectal surgery at UCSF Medical Center, specializes in diseases of the colon, rectum and anus. Her areas of expertise include colorectal and anal cancer, inflammatory bowel diseases such as ulcerative colitis and Crohn’s disease, and pelvic floor disorders. She also is a specialist in treating many of these diseases using laparoscopic (minimally invasive) surgical techniques.

Jeffrey Milsom, MD

Jeffrey Milsom, MD, FACS, is the former Chief of Colon and Rectal Surgery and the Jerome J. Decosse, MD Professor of Surgery at NewYork-Presbyterian/Weill Cornell Medical Center. He serves as the Co-Director of the Center for Advanced Digestive Care. Dr. Milsom is an internationally renowned pioneer in minimally invasive surgery and state-of-the-art laparoscopic and endoscopic technologies for colorectal cancer, Crohn’s disease and other inflammatory bowel disease. Dr. Milsom has been repeatedly recognized by Castle Connolly as one of “America’s Top Doctors,” by New York Magazine as one of New York’s “Best Doctors,” and as a “New York SuperDoctor”, an honor accorded just 5% of all New York physicians.

Professor Mark C Regan
Prof. Mark Regan

Professor Mark C Regan is a consultant General surgeon specialising in Colorectal & Biliary Pancreatic Surgery practising in the Galway Clinic and Galway University Hospitals.

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